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Get Complete Project Material File(s) Now! » Hypermethylated phenotypes Epigenetics is related to DNA methylation and histone modification (acetylation or methylation). These changes only affect the regulation and level of gene expression, but do not alter the nucleotide sequence (56)....
Get Complete Project Material File(s) Now! » IDH-mutant gliomas (astrocytomas and oligodendrogliomas) According to the latest classifications of the WHO, mutations in the IDH genes represent hallmarks of both astrocytomas and oligodendrogliomas. Already from early on, gliomas harboring IDH mutations...