Normal function of IDHs and IDH1/2 mutations in gliomas

Get Complete Project Material File(s) Now! » Hypermethylated phenotypes Epigenetics is related to DNA methylation and histone modification (acetylation or methylation). These changes only affect the regulation and level of gene expression, but do not alter the nucleotide sequence (56)....

Glioma classification by the World Health Organization (WHO)

Get Complete Project Material File(s) Now! » IDH-mutant gliomas (astrocytomas and oligodendrogliomas) According to the latest classifications of the WHO, mutations in the IDH genes represent hallmarks of both astrocytomas and oligodendrogliomas. Already from early on, gliomas harboring IDH mutations...

Advanced serrated lesions of the colon and rectum

Get Complete Project Material File(s) Now! » ADVANCED SERRATED LESIONS OF THE COLON AND RECTUM Introduction Serrated colorectal polyps are defined histologically by a sawtooth-like appearance of the epithelium, and comprise a spectrum of lesions, including hyperplastic polyps, SSA/Ps with...