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Get Complete Project Material File(s) Now! » Notes on Molecular Cell Biology In this chapter we brie y introduce the most important concepts on molecular cell biology that we used throughout the thesis. Notably, we have mainly focused on gene...
Get Complete Project Material File(s) Now! » an overview of the human adaptive immune system Adaptive immunity response has two major types of immune cells: T and B cells. Such cells, also called lymphocytes, have cell surface antigen receptors, respectively...
Get Complete Project Material File(s) Now! » Transport mechanisms in organs involved in calcium homeostasis Bone Bone can be divided in two compartments, namely a rapidly exchangeable pool and a slowly exchangeable pool (Figure 1.2). The rapid pool contains calcium...
Get Complete Project Material File(s) Now! » Nitrogen cycling, river-floodplain system, modelling approach. This chapter reviews studies about nitrogen cycling in the soil-plant-atmosphere system, the nitrate pollution in the aquatic ecosystem, the characterization and limit factors of denitrification function, the...
Get Complete Project Material File(s) Now! » CYP26 Homology Modeling. Characterization of the three-dimensional structure of a protein and, perhaps more importantly, its ligand binding regions can prove crucial to understanding the biological functions of a given drug target or...
Get Complete Project Material File(s) Now! » Cnidarian longevity and regeneration Cnidarians are amongst the longest living animals, and in some cases immortality has been hypothesized. Nevertheless, the range of life span shows a high plasticity within cnidarians. Some polyps...
Get Complete Project Material File(s) Now! » Synergy between ligand and target space An analysis of the drug-target interaction network demonstrated that a given ligand interacts with six protein targets on average at therapeutic concentrations [Mestres et al. (2009)]. Targets...
Get Complete Project Material File(s) Now! » OUTLINE OF THE THESIS In this work we first focused our interest on a better characterization of R. prowazekii adhesins thought to play a major role in adhesion and host cell invasion process....
Get Complete Project Material File(s) Now! » Sources and reaction mechanism of EHs Sources of EHs EHs have been found in many prokaryotic and eukaryotic organisms, including bacteria, fungi, yeast, plants, insects, fish and mammals (Figure 3). The physiological role...
Get Complete Project Material File(s) Now! » Brg1 and Brm transcription factors Brg1 (or Smarca4) and Brm (or Smarca2) are two ATP-dependent SWI/SWF ATP-dependent enzymes containing a bromodomain by which they bind acetylated histones. Brg1 is recruited at the level...