AAC triploid hybrids

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Table of contents

Chapter 1: Bibliographic review 
1.1 Progression of meiosis, as seen through the prism of chromosome association/segregation
1.2 The molecular mechanisms of meiotic recombination
1.3 The progression of meiosis is intertwined with meiotic recombination
1.4 The patterning of meiotic COs formation
1.5 How to deal with the polyploidy situation?
1.6 Ploidy level and recombination frequencies
1.7 Impact of recombination on genetic diversity
1.8 CO frequencies and selection
1.9 How to tackle some of the breeder’s challenges?
Chapter 2: The plant model 
2.1 Origin of Brassica napus
2.2 Relevance for breeding
2.3 Meiosis in Brassica napus
2.4 AAC triploid hybrids
Chapter 3: Objectives of the PhD 
Chapter 4: Deciphering the main source of variation for the meiotic transcriptome of B. napus 
4.1 Introduction
4.2 Manuscript: Homoeologous exchanges drive extensive dosage dependent changes in gene expression and influence allopolyploid genome evolution
4.3 Overview of the transcriptome of Brassica napus meiocytes
4.3.1 Objectives
4.3.2 Details on the experimental design
4.3.3 Details on the mapping
4.3.4 De novo transcriptome assembly
4.3.5 Description of the meiotic transcriptome of B. napus
4.3.6 Partitioning the source of transcriptome variation
4.3.7 Differential gene expression between homoeologs does not result in global sub-genome dominance
4.3.8 Variation of the transcriptome between Darmor-bzh and Yudal
4.3.9 Ploidy change had limited impact on meiotic gene expression
4.3.10 A closer look into PrBn confidence interval
4.3.11 Conclusions and Perspectives
Chapter 5: FANCM 
5.1 Manuscript: FANCM limits meiotic COs in Brassica crops
Chapter 6: General discussion 
6.1 The meiotic transcriptome is highly variable within Brassica napus
6.2 Phenotypic consequences of HEs
6.3 The anti-CO activity of FANCM is conserved in the Brassica
References