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Table of contents
Chapter 1
1. Introduction
2. Entrepreneurship, what definition?
2.1. Division between two conceptions of entrepreneurship
2.1.1. Organising agent through firm creation
2.1.2. Agent bringing change
2.1.3. The contemporary literature on entrepreneurship
2.1.3.1. A variety of disciplines
2.1.3.2. A variety of levels of analyses
2.2. What definition of entrepreneurship should be in use here?
3. Agency and entrepreneurship
4. Who is the entrepreneur?
4.2. The entrepreneurial function: is it always embodied in one person?
4.3. The notion of risk and profit associated to the entrepreneur
4.4. Researchable specificities of the entrepreneur
5. What is the impact of the environment on the entrepreneur and his actions?
5.1. Financing
5.2. Other Institutions
6. How can the entrepreneurial action be observed?
6.1. The notion of time in the entrepreneurial action
6.2. A stage view of the firm early life
6.2.1. Organisational models
6.2.2. How should the innovating organisation be understood
6.3. Researchable characteristics of the entrepreneurial action
7. Conclusion
Chapter 2: The Biotechnology sector: Disentangling inputs and outputs
1. Introduction
2. General context and definition
3. From sciences to technologies
3.1. The scientific revolution behind the emergence of the technology
3.2. Scientific development from the early biological discovery
3.2.1. Genomics
3.2.2. Proteomics
3.2.3. Technologies emerging from the fusion of biology and computer advances
3.2.4. Towards an integrated view of these technologies: the study of systems biology
3.2.5. Stem cells and cell biology
4. Outputs: the consequences on red biotechnology related industries
4.1. Biotechnology in the health sector: overview and definitions
4.2. The pharmaceutical industry
4.2.1. New drugs
4.2.2. Diagnostics
4.2.3. Services
4.2.4. Derived industries: Nutraceuticals and cosmeceuticals
4.2.4.1. Cosmeceuticals
4.2.4.2. Functional foods & nutraceuticals
5. Conclusion
Chapter 3: Empirical background
1. Introduction
2. Methodology
2.1. Research Design
2.1.1. Case study design
2.1.1.1. Research objectives
2.1.1.2. Strategy of research: why opt for a case study research
2.1.1.3. Research design: What type of case study research?
2.1.2. The case selection
2.2. Fieldwork and collection of data
2.2.1. Data collection
2.2.2. Interviews
3. Cases overview
3.1. Alsace Biovalley: An overview
3.1.1. Policy initiative
3.1.1.1. The emergence of a trinational cluster
3.1.1.2. The French historical industry and regional policy
3.1.1.3. The Birth of Alsace BioValley as a convergence of the two initiatives
3.1.2. Institutional support of technology transfer
3.1.3. Financial support available for start-ups
3.1.4. The Research Community
3.1.4.1. The Strasbourg region
3.1.4.2. The Basel Region
3.1.5. The research network in the Strasbourg region
3.1.5.1. Cluster overview
3.1.5.2. Publication activities
3.1.6. Conclusions
3.2. Overview of firms interviewed
3.3. Firm presentations
3.3.1. University spin-offs
3.3.3. Large firm spin-off
3.4. Synthesis of the chapter
4. Concluding comments
Chapter 4: Financial partnering and business model: an interdependent choice
Abstract
1. Introduction
2. Business goals: from the exploitation decision to entry business model
4. The financier-entrepreneur relationship
5. Methodology
5.1. Research design
5.2. Data Gathering
5.3. Data Analysis and operationalisation of the concepts
6. Business model choice: personal experience or regional learning
6.1. Brief history of success and failure of previous generation of start-ups in the cluster
6.2. Business model influences of new firms
6.2.1. Choice of their business model and financing choice and constraints
6.2.1.1. Product model
6.2.1.2. Hybrid or service only models
6.2.1.3. Remarks on financing solutions
6.2.2. Direct and indirect experience
7. Synthesis of the results and discussion
8. Conclusions
Abstract
1. Introduction
2. Theoretical background
2.1. Specificities and constraints of the organising process
3. Methodology
3.1. Research design
3.2. Data Gathering
3.3. Data Analysis and operationalisation of the concepts
4. Detailed analysis of the case studies
4.1.1. Scientists preferences
4.1.2. Business or industrial managers preferences
5. Synthesis of the results and discussion
6. Conclusions
Chapter 6: From science to industry: the involvement of university in academic spin-off formation
Abstract
1. Introduction
2. Theoretical background
2.1. The evolving role of universities
2.2. Public research constraint vs. private research constraint
2.3. Towards a model of university spin-off creation
3. Methodology
3.1. Research design
3.2. Data Gathering
3.3. Data Analysis and operationalisation of the concepts
4. Detailed analysis of the case studies
4.1. Phase I : Research Project to Creation
4.2. Phase II : Firm creation to firm independence (incubation phase)
4.3. Phase III : Firm taking its own R&D path
5. Synthesis of the results and discussion
6. Summary and Conclusions
Conclusion
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