Immunohistochemical staining

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Table of contents

Section 1: OBESITY
Chapter 1: Definition and Epidemiology
Chapter 2: Clinical research and limitations
Chapter 3: Animal models
Section 2: ADIPOSE TISSUE: PHYSIOLOGICAL STRUCTURE & FUNCTION
Chapter 1: Diversity of adipose tissue depots in humans and mice
Chapter 2: Adipose tissue cell types and their functions
I) Adipocytes
II) Adipose-derived stem cells (ADSCs) and preadipocytes
III) Endothelial cells and their progenitors
IV) Adipose tissue immune cells
Section 3: ADIPOSE TISSUE: PATHOPHYSIOLOGICAL STRUCTURE & FUNCTION
Introduction
Chapter 1: Obesity and insulin resistance
I) Insulin signaling pathway in adipocytes
II) Mecanism of insulin resistance in adipocytes
Chapter 2: Obesity and low-grade inflammation
Chapter 3: Obesity and adipose tissue fibrosis
Chapter 4: Obesity and adipose tissue senescence
I) Definition of cellular senescence
II) Replicative cellular senescence
III) Premature cellular senescence
IV) Biomarkers of senescence
V) Adipose tissue senescence in aging and obesity
VI) Adipose tissue cell-type specific senescence
VII) Adipose tissue senescence as a therapeutic target for the treatment of aging- and obesity-related metabolic disorders
Chapter 5: Conclusion
OBJECTIVES
METHODS
RESULTS
Study 1
Study 2
Study 3
Study 4
DISCUSSION