Capacitated sperm

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Table of contents

1 INTRODUCTION
2 MALE FACTOR IN REPRODUCTION 
2.1 Seminal fluid
2.2 Spermatozoa
2.2.1 Spermatogenesis
2.2.2 Capacitation
2.2.3 Acrosome reaction
2.2.4 Fertilization
3 FEMALE FACTOR IN REPRODUCTION 
3.1 Oocyte
3.1.1 Oogenesis
3.2 Embryo development
4 INFERTILITY 
4.1 Unexplained infertility
4.2 Immune infertility
4.2.1 Anti-sperm antibodies
4.2.2 Association of seminal components with female sensitization
4.2.3 Auto-immune aspects in infertility
4.3 Mucosal immunity of the female genital tract
4.3.1 Cervical Mucus
4.4 Treatment of female infertility
4.4.1 Fertility drugs
4.4.2 Reproductive assistance
4.4.3 Intravenous immunoglobulins
4.4.3.1 IVIg and infertility related disorders
5 RESULTS 
5.1 Publications
5.1.1 Anti-sperm antibodies
5.1.2 Disintegration of human sperm and characterization of its antigen
5.1.3 IgG, IgA and IgE reactivities to sperm antigens in infertile women
5.1.4 Female serum immunoglobulins G, A, E and their immunological reactions to seminal fluid antigens
5.1.5 Immunodominant semen proteins I: New patterns of sperm proteins related to female immune infertility
5.1.6 Immunodominant semen proteins II: Contribution of seminal proteins to female immune infertility
5.1.7 Immunodominant semen proteins III: IgG1 and IgG4 linkage in female immune infertility
5.1.8 Pre-eclampsia: a life-threatening pregnancy syndrome
6 FUTURE ASPECTS
6.1 Design of a miniaturized diagnostic tool
6.2 Immuno-Intervention in female immune infertility
7 DISCUSSION 
7.1 Antibody recognition
7.2 Protein markers
7.3 Immunoassay to screen female semen sensitivity
7.4 Immuno-Intervention strategies
8 CONCLUSION 
9 PERSPECTIVES 
10 REFERENCES
11 LIST OF FIGURES
12 LIST OF TABLES 
13 LIST OF ABBREVIATIONS 
14 ANNEXES 
14.1 Publications not related to the topic of female immune infertility
14.1.1 Tumor markers and their use in clinical practice
14.1.2 Indoor long-term persistence of cypress pollen allergenic potency: a 10-month study
14.1.3 Complementarity between microarray and immunoblot for the comparative evaluation of IgE repertoire of French and Italian cypress pollen allergic patients