The differentiation potentials of the NCC in vitro

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Table of contents

LIST OF FIGURES
ABBREVIATIONS
INTRODUCTION
I. THE NEURAL CREST
I.1. Overview of the NC development
I.2. The NC migratory routes and derivatives
I.3. Early steps in NC development: the gene regulatory network of NC induction and specification
I.4. Molecular regulation of the EMT and NCC migration
II. THE DIFFERENTIATION POTENTIALS OF NCC
II.1. Evidence for NCC multipotency in vivo
II.2. The differentiation potentials of the NCC in vitro
II.3. Stem cell properties of NCC
II.4. Maintenance of NC stem cells in adult tissues
II.5. Glia-related postmigratory NC stem cells
III. MESENCHYMAL CELL TYPES
III.1. Endochondral and intramembranous ossification
III.2. Bone matrix mineralization
III.3. Molecular aspects of osteogenesis and chondrogenesis
III.4. Adipogenesis
IV. THE NC AND ITS MESENCHYMAL DERIVATIVES
IV.1. NC and mesoderm interactions in the cranial mesenchyme: role of Six1
IV.2. Evolutionary aspects
IV.3. Regulation of the skeletogenesis of NCC
IV.3.1 Early signals involved in NC mesenchymal fate
IV.3.2 Overview of upstream regulators of Runx2
IV.3.3 Epigenetic mechanisms
V. HOX GENES
V.1. Overview of Hox genes effects on development
V.2. Hox genes and the NC
OBJECTIVES
RESULTS
I. ARTICLE I
II. ARTICLE II
III. ADDITIONAL RESULTS
DISCUSSION
I. SIX1 EXPRESSION IN NC AND MESODERM-DERIVED CRANIOFACIAL TERRITORIES OF THE AVIAN EMBRYO
II. REGULATION OF NC MESENCHYMAL DIFFERENTIATION POTENTIALS BY HOX GENES
REFERENCES