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Table of contents
Summary
Acknowledgments
Published content
Chapter 1: General Introduction
Chapter 2: Targeting the adaptability of heterogeneous aneuploids – Geometrical model of adaptation
Chapter 3: Robustness and Evolvability of a Heterogeneous Cell Populations
Chapter 4: Prediction of drug pair forming an “evolutionary trap” for breast cancer
Chapter 5: Information flow framework for biological network analysis
Chapter 6: Essential genes as evolutionary dead-ends in biomolecular networks
Chapter 7: Experimental investigation of aneuploidy evolvability enhancing potential
Chapter 8: Experimental investigation of aneuploidy impact on intra-nuclear chromosome localization and motility
Chapter 9: ImagePipe: a Python Framework for Biological Microscopy Analysis Pipelines
Chapter 10: Example of application of ImagePipe: import of HS-aggregate related proteins into mitochondria
Chapter 11: General conclusion
Bibliography


