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Table of contents
1. The extracellular matrix
1.1. Structure and function
1.2. Collagens
1.3. Glycoproteins
1.4. ECM – Cells interactions
2. Biomaterials to mimic the ECM
2.1. Biomaterials specifications
2.2. Tissue-specific structural properties
2.3. A concrete example: peripheral nerve regeneration
3. Bionanocomposites for tissue regeneration
3.1. What is a bionanocomposite?
3.2. Nanoparticles
3.2.1. Definition and properties
3.2.2. Synthesis of inorganic nanoparticles
3.2.3. Biofunctionalization of inorganic nanoparticles
3.3. From nanoparticle to bionanocomposite
3.3.1. Bionanocomposite engineering
3.3.2. Application as a biomaterial
3.4. Silica nanoparticle – collagen bionanocomposites
3.4.1. Why combining silica and collagen?
3.4.2. Collagen- Silica for tissue engineering
4. References



