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Table of contents
CHAPTER 1 Introduction
1.1 Scope of thesis
1.2 Stress and neurogenesis in the mammalian central nervous system
1.3 The role of glucocorticoids in hippocampal neuroplasticity
1.4 The role of neurogenesis in hippocampal function
1.5 Functional significance of stress-induced changes to neurogenesis
CHAPTER 2 Regulation of adult hippocampal neurogenesis by GR in newborn neurons
2.1 Abstract
2.2 Introduction
2.3 Results
2.4 Discussion
2.5 Materials and Methods
2.6 Figures and Legends
CHAPTER 3 Functional contributions of the glucocorticoid receptor in adult neurogenesis
3.1 Abstract
3.2 Introduction
3.3 Results
3.4 Discussion
3.5 Materials and Methods
3.6 Figures and Legends
CHAPTER 4 Introduction to general discussion
4.1 Introduction to general discussion
4.2 CreERT2-mediated GR gene inactivation in neural progenitor cells
4.3 Glucocorticoid receptor signaling in the neurogenic niche
4.4 GR signaling in adult-born granule cells: implications for stress-related brain disorders
4.5 Future directions
CHAPTER 5 References




