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Get Complete Project Material File(s) Now! » Hepatic stem cells Hepatic stem cells have been hypothesized to exist in the liver, taking part in its regeneration after injury. In rat, “oval cells” were observed in injury where hepatocytes did not...
Get Complete Project Material File(s) Now! » Basic Mechanisms of the Mammalian Cell Cycle and Circadian Cell Clock Systems In this Section we brie y expose some of the basic molecular mechanisms of the mammalian cell cycle and cellular clock...
Get Complete Project Material File(s) Now! » LncRNA transcription and the associated chromatin signature The majority of eukaryotic lncRNAs are produced by RNA polymerase II, with some exceptions such as the murine heat-shock induced B2-SINE RNAs (Espinoza et al., 2007),...
Get Complete Project Material File(s) Now! » Loss of heterozygosity (LOH): a common cause of genome alteration in somatic cells As the cells in our tissues are being renewed throughout life, our somatic cells should faithfully preserve the integrity of...
Project topics and materials
Get Complete Project Material File(s) Now! » Cancer development Cancer development is a very complex process, which can significantly di↵er between cancer types and stages of the disease. There are approximately two hundreds of genes associated with cancer in contemporary...
Get Complete Project Material File(s) Now! » Possible applications in the medical field The advent of high throughput sequencing techniques revolutionized the medical field allowing gene expression comparisons between healthy and disease conditions. The aim of these studies was mainly...
Get Complete Project Material File(s) Now! » Chronic inflammation in tumor initiation and progression: Chronic inflammation is one of the hallmarks of cancer [324]. Indeed, 25% of human malignancies are related to chronic inflammation [325]. As early as 1863, the...
Get Complete Project Material File(s) Now! » DEBATABLE PHYSIOLOGICAL LEVELS: TECHNICAL ISSUES FOR ANEUPLOIDY DETECTION Many studies have investigated the karyotype of cells, organs and tissues and it was initially proposed that a certain level of aneuploidy could be tolerated...
Get Complete Project Material File(s) Now! » qPCR evaluation of copy number across repetitive element targeting gRNAs - The qPCR reactions were generated using the KAPA SYBR FAST Universal 2X qPCR Master Mix (Catalog #KK4602) according to the manufacturer’s instructions....
Get Complete Project Material File(s) Now! » Soil contamination with heavy metals & phytoremediation Pollution of soil with heavy metals becomes a fast-rising issue in many places due to a vast scope of anthropogenic activities (Pant et al., 2014). The...