Different forms of Ovarian Cancer

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Table of contents

INTRODUCTION 
I. Ovarian cancer
1. The disease
2. Biomechanical process during cancer progression
3. Current diagnostics and new developments
4. ‘Classic’ Ovarian Cancer treatments
5. ‘New’ Ovarian Cancer treatments
6. Nanomedicines and Ovarian Cancer
II. Epigenetics
1. Definition
2. Transcription activation mark (H3K4)
3. Transcription repression mark (H3K27)
4. Heterochromatin mark (H3K9)
5. Current knowledge of the effect of epigenetics in ovarian cancer
III. Selenium in cancer treatment
1. Dietary window of selenium and metabolism
2. Low dose of selenium triggers ROS scavenging
3. High doses of selenium are cytotoxic
4. Effect of selenium on epigenetic mechanisms
5. Selenium Nanoparticles
IV. Objectives
SELENIUM NANOPARTICLES TRIGGERS ALTERATIONS IN OVARIAN CANCER CELLS BIOMECHANICS 
I. Presentation of the article
II. Article
SELENIUM NANOPARTICLES INDUCE GLOBAL HISTONE METHYLATION CHANGES IN OVARIAN CANCER CELLS 
I. Presentation of the article
II. Article
CU ISOTOPE RATIOS ARE MEANINGFUL IN OVARIAN CANCER DIAGNOSIS 
I. Presentation of the article
II. Article
CONCLUSION AND PERSPECTIVES 
I. Conclusions
II. Perspectives
REFERENCES