Genetic influences on DNA methylation

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Table of contents

1. The roots of obesity and its disastrous consequences
1.1. Obesity: a huge health and economic burden
1.2. The relative contribution of genetics and the environment to obesity
1.3. Genome-wide association studies (GWASs) and the problem of missing heritability
1.4. Reconciling genetics and the environment with epigenetic mechanisms
2. Epigenetic modifications: focus on DNA methylation
2.1. Overview of epigenetics
2.2. Function and information content of DNA methylation in the CpG context
3. Studying DNA methylation in the context of obesity
3.1. Measuring DNA methylation
3.2. What we already know about DNA methylation in the context of obesity
3.3. Challenges to face

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