Glycosaminoglycans (GAGs) chains

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Table of contents

Chapter 1
1. Proteoglycans
1.1 Glycosaminoglycans (GAGs) chains
1.2 Classification of the PGs
1.3 Heparan sulfate proteoglycans (HSPG)
1.3.1 HS synthesis
1.3.2 Syndecans
1.3.3 Glypicans
1.3.4 Perlecan
1.3.5 Betaglycan/TGFβ type III receptor
1.4 Chondroitin sulfate proteoglycans (CSPG)
1.4.1 Decorin
1.4.2 Biglycan
1.4.3 CSPG4/NG2
1.4.4 Aggrecan
1.4.5 Versican
Chapter 2
2. Biosynthesis of GAG chains
2.2 Synthesis of the tetrasaccharide linker
2.3 Elongation of the CS chains
2.4 Elongation of the HS Chains
2.4 Regulation of PG synthesis
Chapter 3
3 Xylosyltransferase
3.1 Specificity of the xylosyltransferase
3.2 Structure of the XT-I and XT-II
3.4 Structural/Functional relationship
3.4 Purification of the XT from tissue source
3.5 Purification of the XT from cellular source as cDNA cloning
3.6 Intracellular localization
3.7 XT activity analysis
3.8 XT in health and disease
3.9 XT-I and XT-II genetic variants
3.10 Regulation of Xylosyltransferase
Chapter 4
4. Fam20B
4.1 Structure of Fam20B
4.4 Interaction of phosphoxylose with GalT-I, GalT-II, GlcAT-I, EXTL2 and ChGn-I
Chapter 5
5. Xylosides
5.1 GAG priming xylosides
5.2 GAG inhibiting xylosides