Laser-capture microdissection

For more info about our services contact : help@bestpfe.com

Table of contents

I. STATE OF THE ART
1. MYASTHENIA GRAVIS
1.1 GENERALITIES
1.1.1 HISTORY
1.1.2 EPIDEMOLOGY
1.1.3 SYMPTOMS AND DIAGNOSIS
1.2 PATHOPHYSIOLOGICAL MECHANISMS IN MG
1.2.1 THE NEUROMUSCULAR JUNCTION UNDER PHYSIOLOGICAL CONDITIONS
1.2.2 PATHOGENIC MECHANISMS IN MG
1.2.3 GENETIC PREDISPOSITION
1.2.4 TREATMENTS
1.3 EXPERIMENTAL AUTOIMMUNE MG
1.4 NEW POTENTIAL THERAPIES
2. THYMUS
2.1 STRUCTURE AND FUNCTION
2.1.1 GENERALITIES
2.1.2 THYMIC CELLS
2.1.3 T CELLS: MATURATION BY NEGATIVE AND POSITIVE SELECTION
2.2 PATHOLOGICAL ROLE
2.2.1 THYMIC DISORDERS
2.2.2 THYMOMA-ASSOCIATED MG
2.2.3 THE HYPERPLASTIC THYMUS IN MG
3. CHEMOKINES
3.1 GENERAL PROPERTIES
3.1.1 STRUCUTRE AND CLASSIFICATION
3.1.2 CHEMOKINE RECEPTOR SIGNALING
3.2 PHYSIOLOGICAL ROLE OF CHEMOKINES
3.2.1 LYMPHOCYTE HOMING
3.2.2 THYMOPOIESIS
3.3 PATHOLOGICAL ROLE OF CHEMOKINES
3.3.2 CHEMOKINES IN MG THYMUS
II. AIM OF THE STUDY
III. RESULTS
Article 1
Article 2
Article 3
Article 4
IV. GENERAL CONCLUSION
V. PERSPECTIVES
VI. REFERENCES