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Table of contents
CHAPTER I. AN OVERVIEW TO LIPID ACCUMULATION
I. OLEAGINOUS MICROORGANISMS
II. A GLANCE TO LIPID METABOLISM
III. GENERAL ASPECTS OF LIPID ACCUMULATION BIOPROCESSES
IV. CONCLUSIONS
V. REFERENCES
CHAPTER II. MODELING AND PROCESS OPTIMIZATION
I. UNSTRUCTURED MODELING OF LIPID ACCUMULATION
II. MODELING METABOLISM
III. CONTROL OF BIOPROCESSES
IV. STATE ESTIMATION
V. CONCLUSIONS
VI. REFERENCES
CHAPTER III. RESULTS
I. INTRODUCTION
II. REDUCTION OF METABOLIC MODELS BY POLYGONS OPTIMIZATION METHOD APPLIED TO BIOETHANOL PRODUCTION WITH CO-SUBSTRATES
III. DYNAMIC METABOLIC MODELING OF LIPID ACCUMULATION AND CITRIC ACID PRODUCTION BY YARROWIA LIPOLYTICA
IV. MODELING AND OPTIMIZATION OF LIPID ACCUMULATION DURING FED-BARCH FERMENTATION BY YARROWIA LIPOLYTICA FROM GLUCOSE UNDER NITROGEN DEPLETION CONDITIONS
V. MULTI-OBJECTIVE PARTICLE SWARM OPTIMIZATION (MOPSO) OF LIPID ACCUMULATION IN FED-BATCH CULTURES
VI. SOFT-SENSORS FOR LIPID FERMENTATION VARIABLES BASED ON PSO SUPPORT VECTOR MACHINES (PSO-SVM)
VII. DISCUSSION AND CONCLUSIONS
VIII. REFERENCES
CHAPTER IV. CONCLUSIONS AND PERSPECTIVES
REFERENCES
