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Table of contents
GENERAL INTRODUCTION
1. Pig production
a. Pig data in the World
b. Data on pig production in Europe, Italy and France
c. Pig production systems
d. Antibiotic practises in pig herds and the antibiotic resistance issue
i. Antibiotics consumption data in Europe
2. The gut microbiota
a. The gut microbiota in pigs
b. Gut microbiota and gut health: what is a healthy gut microbiota?
i. Eubiosis, dysbiosis and symbiosis
ii. Probiotics, Prebiotics and Synbiotics
iii. Next-generation probiotics from microbiota studies: the example of Faecalibacterium prausnitzii
3. Health and disease
a. Diseases in pig production
b. Weaning enteric diseases
i. The Enterotoxigenic Escherichia coli infection in piglets
ii. The MUC4 and FUT1 candidate genes in piglets
Paper I
1. Abstract
2. Introduction
3. Results
4. Discussion
5. Conclusions
6. Methods
7. Declarations
8. References
9. Supplementary information
Paper II
1. Abstract
2. Introduction
3. Materials and Methods
4. Results
5. Discussion
6. Declarations
7. References
8. Supplementary information
GENERAL DISCUSSION
1. On microbiota’s role in the post-weaning diarrhoea of piglets
2. On technical choices for the study of gut microbiota in our work
3. Summary of challenges and opportunities for the prevention of diarrhoea at weaning
CONCLUSIONS



