PWI in ischemic stroke

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Table of contents

Chapter 1: Background and state of the art
1.The brain and ischemic stroke
1.1.The anatomy and vasculature of the brain
1.2.Epidemiology of stroke
1.3.Pathophysiology of ischemic stroke
1.4.Treatment of ischemic stroke
1.5.Functional assessment scale for the evaluation of ischemic stroke
1.5.1.National Institutes of Health Stroke Scale (NIHSS)
1.5.2.Modified Rankin Scale (mRS)
2.Utilization of MRI in ischemic stroke evaluation
2.1.Basic concepts of MRI
2.1.1.T1 and T2 relaxation and contrast
2.1.2.Spin echo sequence
2.2.Common MRI sequences used in ischemic stroke
2.2.1.DWI
(1). Principle of DWI
(2). DWI in ischemic stroke
2.2.2.PWI
(1). Principle of PWI
(2). PWI in ischemic stroke
2.2.3.PWI-DWI mismatch
2.2.4.T2-FLAIR sequence
2.2.5.T2*-weighted image
2.2.6.MR angiography
3.Synopsis of THRACE study
3.1.Objective
3.2.Patients inclusion
3.3.Procedures of the study
3.4.Main results of THRACE study
4.Working environment
4.1.Laboratory IADI
4.2.CIC-IT
Chapter 2: The role of MRI in the evaluation of brain tissue viability
Introduction
Article 1
Discussion
Résumé en français
Chapter 3: Pretreatment ischemic stroke lesional volume and clinical outcome
Introduction
Article 2
Article 3
Discussion
Résumé en français
Chapter 4: Ischemic stroke lesional location and functional outcome
Introduction
Article 4
Discussion
Résumé en français
Chapter 5: General discussion
Summary of the results
Strengths
Weaknesses
Implications for the future research
References