Regulation of the muscle progenitor pool

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Table of contents

Acknowledgements
Table of Contents
Summary
Resumé
Zusammenfassung
Gene Nomenclature and Abbreviations
State of the ar
Synopsis
1 – Skeletal muscle development
1.1 – Skeletal muscle specification in the head, trunk and limbs
1.2 – Limb muscle formation
2 – Embryonic, foetal and adult myogenesis
3 – Regulation of the muscle progenitor pool
3.1 – The balance between proliferation and differentiation
3.2 – Signalling pathways
3.2.1 – Notch signalling pathway
3.2.2 – BMP signalling pathway
3.2.3 – Crosstalk between Notch and TGFβ/BMP signalling pathways
4 – Muscle as mechanical tissue
4.1 – Importance of muscle contraction during development
4.2 – The mechano-sensitive gene Yap and its role in myogenesis
Results
Publications
1 – The interplay between NOTCH and BMP signalling pathways is different during proliferation and differentiation during foetal myogenesis Synopsis
Abstract
Introduction
Results
Discussion
Materials and Methods
2 – Muscle contraction activates YAP and NOTCH signalling and thus regulates the pool of muscle progenitor cells during foetal myogenesis Synopsis
Abstract
Introduction
Results
Discussion
Materials and Methods
Additional Information
Discussion and Perspectives
Conclusion
References