(Downloads - 0)
For more info about our services contact : help@bestpfe.com
Table of contents
SUMMARY ACKNOWLEDGEMENTS
INTRODUCTION
Prologue: the paradigm of the X-inactivation centre
Review 1: X-chromosome inactivation: new insights into cis and trans regulation (review published in Current Opinion in Genetics & Development, 2015)
Review 2: Chromatin architecture and gene regulation during X-chromosome inactivation (review in preparation for Annual Review of Genetics, 2018)
Review 3: From promoters and enhancers to TADs and regulatory landscapes across development, disease and evolution (unpublished review)
RESULTS
Article 1: Predictive polymer modelling reveals coupled fluctuations in chromosome conformation and transcription (published in Cell, 2014)
Article 2: Evidence for cross-TAD communication during X-inactivation via the noncoding Linx locus (manuscript in preparation)
Article 3: Genetic dissection of TAD organisation and function at the X-inactivation centre (manuscript in preparation)
Methods for Article 2 and Article 3
DISCUSSION & PERSPECTIVES
REFERENCES
APPENDICES
Supplementary Results
Article 4: Xist-dependent imprinted X inactivation and the early developmental consequences of its failure (published in Nat Struct Mol Biol, 2017)
