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Table of contents
Part I – General introduction
1 Bioactive peptides from milk proteins
2 GABAergic system and α-casozepine
3 Behavioural and neural bases of anxiety
4 Rodents’ models of anxiety
Part II – Personal work
1 Objectives of the research project
2 Evaluation of the mices based on their basal levels of anxiety
3 Modulation of neural activity in mice induced by α-casozepine
4 Evaluation of the anxiolytic activity of, and the modulation of brain activity by YLGYL, a derivative from α-casozepine
5 Investigations concerning the mediation of anxiolytic-like properties of α-casozepine
Part III – General discussion and conclusion
1 Deciphering the central mode of action of α-casozepine
2 Conclusion and Persectives
Part IV – Annex
1 Résumé substantiel
2 List of communications


