Mathematical modeling of occupational exposure to chemicals

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Table of contents

GENERAL INTRODUCTION
I. Context and general objectives
I.1. State of the art
I.2. Study site
II. Literature review
II.1. Metallic pollution in Sfax:
II.2. Human health risk assessment
II.2.1. Presentation of the approach
II.2.2. Hazard identification
II.2.2.1. Trace metallic elements
II.2.2.2. Identification of potential hazards of the selected trace metallic elements
a. Health effects of chronic exposure to Al by the inhalation route
b. Health effects of chronic exposure to Cr by the inhalation route
c. Health effects of chronic exposure to Ni by the inhalation route
d. Health effects of chronic exposure to Cu by the inhalation route
e. Health effects of chronic exposure to Pb by the inhalation route
f. Health effects of chronic exposure to Zn by the inhalation route
II.2.2.3. Mixture and interactions of metals
II.2.2.4. Toxicokinetics: Physiologically Based PharmacoKinetic models
II.2.3. Exposure assessment
II.2.3.1. Occupational exposure to trace metallic elements
II.2.3.2. Mathematical modeling of occupational exposure to chemicals
a. Well mixed box model
b. Near field –far field model
c. Parameters calculations
i. Ventilation rate “Q”
ii. The air volume “V”
iii. Generation rate “G”
1) The mass balance method
2) The emission factor method
 Emission factors for electric arc welding
 Emission factors for electroplating
 Emission factors for Resistance sport welding
3) Other model-specific parameters:
II.2.4. Risk characterization methods for chemical mixtures
III. Specific scientific objectives
IV. Bibliography