Identification of Bifidobacteria as novel activators of AhR pathway in human intestinal epithelial cells 

Get Complete Project Material File(s) Now! » Development and age-related variation of gut microbiota Despite the variations due to environmental factors, the microbiota of healthy adults, could be still defined as quite stable. However, during lifetime from newborn to elderly,...

CORONAVIRUS INTERSPECIES TRANSMISSIONS AND ADAPTATION TO A NEW HOST

Get Complete Project Material File(s) Now! » Human Coronaviruses associated with mild respiratory diseases The first isolated human Coronaviruses were HCoV-229E and OC43 in 1967, from patients with upper respiratory tract infections (Almeida and Tyrrell, 1967). These two human Coronaviruses...

« The transcription factor NRF2 regulates matrisome gene expression and collagen fibrillogenesis in human skin fibroblasts “

Get Complete Project Material File(s) Now! » Maturation in the Golgi apparatus and secretion of the collagen molecule Procollagen molecules are further translocated to the Golgi apparatus, which ensures accurate procollagen glycosylation and trafficking. Before their transport to the extracellular...

Characterization of diseases pressure in the Bordeaux vineyard, a focus on 2010-2018.

Get Complete Project Material File(s) Now! » Powdery Mildew (PM) Powdery Mildew was the first American pathogen to be introduced in Europe. The disease was first reported in England in 1845 (Tucker, 1845), then in France in 1848, near Paris....

EARLY MATERNAL IMMUNE ACTIVATION ALTERS MICROGLIA DEVELOPMENTAL TRAJECTORY AND INDUCES LONG-TERM BEHAVIOURAL ALTERATIONS IN THE OFFSPRING IN A SEXUALLY DIMORPHIC MANNER 

Get Complete Project Material File(s) Now! » Microglial precursors differentiation CSF1R signaling is known as essential for microglial development and maintenance (Chitu et al. 2016; Chitu and Stanley 2017). Indeed, during embryogenesis, YS macrophages depend on CSF1R signaling for their...

Force production and regulation by the cytoskeleton

Get Complete Project Material File(s) Now! » Stress fibers formation and dynamics One of the major contractile elements in cells are the stress fibers (Kassianidou & Kumar, 2015; Pellegrin & Mellor, 2007; Vallenius, 2013). They were observed decades ago as...

Comparison between FW quality and optimal conditions for AD treatment

Get Complete Project Material File(s) Now! » Information characterizing data origins In order to perform a statistical analysis, FW characteristics data were sorted considering three categories of possible variation factors: continents of the analysed FW, collection sources and season of...

INFLUENCE OF THE VARIABLE AMINO ACIDS DURING THE DOCKING OF THE DMS

Get Complete Project Material File(s) Now! » From defensive properties to interesting bioactivities Thanks to their defensive properties, furanocoumarins exhibit a large range of bioactivities such as photosensitiser, P450-inhibitors, antifungal, antibacterial and antiviral activities, but also antioxidant, anti-inflammatory, anticancer, anticonvulsant,...

Molecular mechanisms in the development of hepatocellular carcinoma 

Get Complete Project Material File(s) Now! » Alcohol Although the pathogenic mechanisms underlying the initiation of alcohol-induced tumorigenesis have been well defined (118,119) , the alcohol-related signaling pathways involved in tumor promotion and progression are poorly understood. Induction of cytochrome...

Mechanisms involved in the maintenance of genome integrity

Get Complete Project Material File(s) Now! » Control of the G1/S transition: the E2F/RBR pathway As previously described, CYCD/CDKA complexes the first CDK/Cyclin complexes activated for cell cycle onset. Consistently, expression of a number of CYCD responds to external cues...