Large Bio Medical Databases as drivers of creativity: An analysis of the case of the Pharmaceutical Industry.

Get Complete Project Material File(s) Now! » Some recent examples of scientific discovery: HIV and stem cells Let us look at one example: human immunodeficiency virus (HIV) has infected more than 78 million people since 1981, it is the cause...

Detection of loci under selection in Fagus Sylvatica along an altitudinal gradient: an outlier experimental approach

Get Complete Project Material File(s) Now! » SPEED OF ADAPTATION OF FOREST TREES TO CLIMATE CHANGE Cycles of glacial and interglacial periods occurred on the earth’s surface for at least the past 2.7 million years, with glacial periods being characterized...

TOWARDS ACCURATE AND EFFICIENT AMINOACID pKa PREDICTIONS USING CALCULATED ATOMIC CHARGES

Get Complete Project Material File(s) Now! » Asparagine Deamidation in Triosephosphate Isomerase In 1980, Gracy et al. detected asparagine deamidation in human TPI, on two dis-tinct asparagines with the sequence of LysMetAsn(15)GlyArg and ValThrAsn(71)GlyAla [30]. Their ndings explained previously observed...

EMD-BASED FEATURE EXTRACTION AND SELECTION FOR SUBJECTS CLASSIFICATION 

Get Complete Project Material File(s) Now! » The main components of the postural system The tonic postural system has two types of entries. The input related to external in-formation and those related to interior information. The sensory input provides the...

SystemC Multi-Disciplinary Virtual Prototyping (MDVP) Simulator Prototype 

Get Complete Project Material File(s) Now! » Discrete Event (DE) Simulation Kernel The DE simulation kernel of SystemC provides the core features for the elaboration and simulation of models [25]. Elaboration creates the data structures required to support the simulation...

Distinction between drug delivery systems according to their mechanism of drug release

Get Complete Project Material File(s) Now! » Paenteral drug delivery The parenteral route can refer to any administration route allowing the avoidance of the gastrointestinal tract and therefore the first-pass effect of drugs. Nevertheless, common usage more closely associates the...

Effect of different parameters on the corrosion behavior of 70Cu-30Ni alloy and Al brass

Get Complete Project Material File(s) Now! » COOLING WATER SYSTEMS IN POWER SUPPLY FACILITIES This PhD manuscript focuses on the study of the corrosion of copper alloys used in the production of piping material for the electricity-generating plants, like fossil...

Prediction of drug pair forming an “evolutionary trap” for breast cancer

Get Complete Project Material File(s) Now! » Targeting the adaptability of heterogeneous aneuploids – Geometrical model of adaptation The mathematical modelling of the relationship between the robustness and evolvability of heterogeneous cell populations started as an observation that in the...

Viscosity Solutions for Integro-Differential Equations

Get Complete Project Material File(s) Now! » Strong Maximum Principle (Chapter 3) Our study began with an investigation of the Strong Maximum Principle for viscosity solutions of second-order non-linear parabolic integro-differential equations [Cio]. It is worth mention-ing that Strong Maximum...

Strategy Based on the Progressive Refinement of the Internal Convergence Criteria 

Get Complete Project Material File(s) Now! » Nuclear Reactor Core as a Multiphysic System In this section, the concept of multiphysics of nuclear reactor cores is introduced from a physics-based point of view. In the first part, some general examples...